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REPORT SULLE ATTIVITÀ SVOLTE
REPORT ON THE ACTIVITIES UNDERTAKEN
Corso di dottorato / PhD Program Scienze chimiche e dei materiali
Curriculum (se previsto / if applicable) _______________________________
Cognome / Family Name Guazzelli
Nome / Name Elisa
Data nascita / Date of Birth 26/04/1989
Luogo nascita / Place of Birth Castelnuovo di Garfagnana
Data di rilascio del titolo / Date of issue of the certificate 12/03/2017
Eventuale valutazione (se prevista) / Subsequent evaluation (if applicable) ___________________
Supervisore / Supervisors Prof G. Galli, Dr E.Martinelli
Commissione di esame finale (Nome, cognome e ente di afferenza) / Final exam board (Name,
Family Name and relevant department) Katia Sparnacci (Univ. del Piemonte orientale), Simona
Bronco (IPCF-CNR Pisa), Valentina Domenici (Università di Pisa), Chiara Gabbiani (Università di
Pisa) e Fabio Di Francesco (Università di Pisa)
ATTIVITÀ FORMATIVE / FORMATIVE ACTIVITIES
I anno di corso / I course year (anno accademico / academic year 2014/2015 DENOMINAZIONE DEL CORSO / NAME OF THE COURSE DURATA / DURATION (in ore / in hours) SEDE / LOCATION (indicare Università o altra sede di svolgimento / indicate the university or other course location) DOCENTE / PROFESSOR (nome e cognome / name and family name) VOTAZIONE / FINAL MARK GIUDIZIO / EVALUATION LINGUA UTILIZZATA (italiano, inglese, altra lingua / Italian, English or other languages) Corsi del dottorato
frequentati/ Doctorate courses attended Dicroismo Circolare Elettronico e Chiralità Supramolecolare 4 DCCI UNIPI Gennaro Pescitelli Italiano Radiofarmaci e Medicina Nucleare 2 DCCI UNIPI Debora Petroni Italiano
Altri corsi/ Other courses Chimica dei nanomateriali 48 DCCI UNIPI Andrea Pucci Idoneità Italiano
2 Seminari di ricerca/Research seminars (argomento e ore di svolgimento / topic and number of hours carried out)
1. 13/01/2015 (1h)Prof. U. Kleinekathofer “Quantum coherences and dephasing in Biosystems”
2. 30/01/2015 (1h)Dott.ssa M. Pastore “First Principle Modeling of optical, spectroscopic and charge generation properties in molecule/semiconductor heterointerfaces”
3. 18/02/2015 (1h) Prof. M. Prato “Chimica e Nanoscienze: nuove frontiere per la medicina e l’energia”
4. 20/02/2015 (1h) Prof. V. Passarelli “Rhodium and iridium complexes with aminophosphano ligands: synthesis, structural characterisation and reactivity” 5. 01/04/2015 (1h) Prof F.A. Gianturco “The dawn of chemistry: the making of early
universe molecules”
6. 11/05/2015 (1h) Prof S. Campagna “Towards artificial photosynthesis: light harvesting antenna systems and photochemical water splitting”
7. 25/05/2015 (1h) Dr A. Pucci "Polymers that play with light"
8. 27/05/2015 (1h) Prof D. Diamond "Stimuli-Responsive Materials and Biomimetic Fluidics: Key Building Blocks of Futuristic Autonomous Chem/Bio-Sensing Platforms"
9. 18/06/2015 (1h) Dr R. Sokolova "Electrochemistry and spectroelectrochemistry of bioactive compounds”.
10. 19/06/2015 (1h) Dr M. Bortoluzzi "Antenna-ligands in photoluminescent lanthanide complexes" … PERIODO DI SVOLGIMENTO (da ___ a ____ / a ___ to ___) ENTE OSPITANTE (nome, luogo ed eventuale supervisore / name, location
and subsequent supervisor)
ATTIVITÀ SVOLTE E RISULTATI ACTIVITIES CARRIED OUT AND RESULTS
Esperienze di ricerca presso altre strutture / Research experience in other institutions Attività o borse all’estero/Training or Scholarship abroad
3 II anno di corso / I course year (anno accademico / academic year 2015/2016
DENOMINAZIONE DEL CORSO / NAME
OF THE COURSE DURATA / DURATION (in ore / in hours) SEDE / LOCATION (indicare Università o altra sede di svolgimento / indicate the university or other course location) DOCENTE / PROFESSOR (nome e cognome / name and family name) VOTAZIONE / FINAL MARK GIUDIZIO / EVALUATION LINGUA UTILIZZATA (italiano, inglese, altra lingua / Italian, English or other languages) Corsi del Dottorato frequentati/ Doctorate Courses Attended
Short
course:
Scientific English
16 DCCI UNIPI Adrian Wallwork
English
Altri corsi/ Other Courses
Principi
e
applicazioni della
spettroscopia
Raman (e prova
pratica
dello
strumento
XploRA™PLUS)
6 DCCI UNIPI S. Gay Italiano
Seminari di ricerca/Research Seminars (argomento e ore di svolgimento / topic and number of hours carried out)
1. 6/07/2016 (1h) Prof R. Simonutti - Sintesi e self-assembly di copolimeri a blocchi
anfifilici
2. 20/06/2016 (1h) Prof. El-Refaie Kenawy - Antimicrobial Polymers: Chemistry
and Applications
3. 21/04/2016 (1h) Dr. A. Rogalev - Polarization dependent X-ray spectroscopy:
recent advances
4. 5/04/2016 (1h) Dr. M. Bandini - Catalytic Manipulation of Indole in Bologna
5. 4/03/2016 (1h) Prof. S. Zacchini - Molecular Metal Carbonyl Nanoclusters
6. 1/03/2016 (1h) Dr. M. Górecki - Circular Dichroism as an Assistant for Solving
Structural Problems in Solution and Solid-State
7. 9/02/2016 (1h) Dr. F. Pineider - Molecole e nanostrutture per la
magnetoplasmonica
8. 26/01/2016 (1h) Dr. G. Pascali - Impatto delle tecniche microfluidiche in
(radio)chimica
PERIODO DI SVOLGIMENTO (da ___ a ____ / a ___ to ___) ENTE OSPITANTE (nome, luogo ed eventuale supervisore / name, locationand subsequent supervisor)
ATTIVITÀ SVOLTE E RISULTATI ACTIVITIES CARRIED OUT AND RESULTS Esperienze di ricerca presso altre strutture / Research experience in other institutions Attività o borse all’estero/Trainin g or Scholarship abroad
4 III anno di corso / III course year (anno accademico / academic year 2016/2017
DENOMINAZIO NE DEL CORSO / NAME OF THE COURSE DURATA / DURATION (in ore / in hours) SEDE / LOCATION (indicare Università o altra sede di svolgimento / indicate the university or other course location) DOCENTE / PROFESSOR (nome e cognome / name and family name) VOTAZIONE / FINAL MARK GIUDIZIO / EVALUATION LINGUA UTILIZZATA (italiano, inglese, altra lingua / Italian, English or other languages) Corsi del Dottorato
frequentati/ Doctorate Courses Attended Short course: Magnetic molecular materials
9 DCCI UNIPI G. Poneti
Altri corsi/ Other Courses
Seminari di ricerca/Research Seminars (argomento e ore di svolgimento / topic and number of hours carried out)
1. 29/11/2017 (4h)– Dalla ricerca all’impresa
2. 28/09/2017 (1h) Dr. R. Paterni – Comunicazione, management and leadership
3. 09/09/2017 (1h) Prof. C. Landis – Valency and bonding as revealed by NBO methods
4. 07/09/2017 (1h) Prof. C. Landis – Methods for operando studies of catalysis 5. 13/07/2017 (1h) Prof. S. Slomkowski – Polysiloxane microcapsules,
preceramic microspheres and their ceramized derivatives
6. 01/06/2017 (1h) Prof. T.E. Hogen-Esch – Synthesis of Nano-scale Structured Tunable Membranes Based on Polystyrene Sulfonic acid Polyvinylidene fluoride Blends for Proton Exchange Fuel Cells and Ultrafiltration.
7. 15/05/2017 (1h) Prof. C. Boyer – Design of Functional Polymers for Advanced Applications
8. 23/01/2017 (1h) Dr. J.-W. Lee – A study on the interfacial properties of nanoparticles-contained carbon fiber reinforced composite materials / antifouling applications
9. 19/12/2016 (1h) Dr. D. Perego – Integrated Li-ion microbatteries
10. 13/12/2016 (1h) Dr. O. Maury – Puzzling Applications of Lanthanide Luminescence in crystals, magnets, proteins, and cells
11. 23/11/2016 (1h) Dr. E. Juszyńska-Gałązka – Investigation of the polymorphism and dynamics of glass-forming in soft matter compounds with one phenyl ring PERIODO DI SVOLGIMENTO (da ___a ____ / a ___ to ___) ENTE OSPITANTE (nome, luogo ed eventuale supervisore / name, location
and subsequent supervisor)
ATTIVITÀ SVOLTE E RISULTATI ACTIVITIES CARRIED OUT AND RESULTS Esperienze di ricerca
presso altre strutture / Research experience in other institutions Attività o borse all’estero/Training or Scholarship abroad 04/01/2017 – 26/06/2017
University of Toulon, France, Prof. C. Bressy
RAFT synthesis of amphiphilic hydrolysable copolymer. Formulation and characterization of antifouling/fouling-release marine coatings.
5 PERIODO DI SVOLGIMENTO (da ___ a ____) ENTE OSPITANTE (nome, luogo e eventuale supervisore)
ATTIVITÀ SVOLTE E RISULTATI
Esperienze di ricerca presso altre strutture / Research experience in other institutions Attività o borse all’estero / Training or Scholarship/s abroad 04/01/2017 – 26/06/2017 University of Toulon, France, Prof. C. Bressy
RAFT synthesis of amphiphilic hydrolysable copolymer. Formulation and characterization of antifouling/fouling-release marine coatings.
TITOLO DELLA TESI / TITLE OF THE PHD THESIS
Designed amphiphilic polymers: self-assembly and nanostructure in solution and thin film
PROGETTO DI RICERCA/RESEARCH PROJECT (descrivere sinteticamente / please provide a short
description)
Different classes of amphiphilic copolymers were designed to incorporate both hydrophilic and hydrophobic components which could enable investigation of their distinct self-assembly and nanostructure over various states from solution in selective solvents to surface of thin solid films. By taking advantage of the controlled nature of the reversible-deactivation radical polymerisation methods, namely ATRP and RAFT, copolymers with diverse chemical architectures and structures were prepared with a tailored and varied philic/phobic balance. Comonomers, such as those based on a hydrophilic polyethyleneglycol methacrylate, a hydrophobic and lipophobic fluoroalkyl acrylate, a hydrophobic polysiloxane methacrylate, and two hydrolysable
trialkylsilyl methacrylates, were selected in order to provide the materials with functional and responsive characters in addition to the capacity of self-assembling and structuring over length scales.
Dynamic light scattering (DLS) and small angle neutron scattering (SANS) experiments confirmed the formation of nanosized, unimer micelles at room temperature which turned into collective nano-to-microsized aggregates above a critical transition temperature. Fluorescent molecular probes were used to further investigate the properties of the nanostructures obtained. Molecular dynamics (MD) simulations were carried out to evaluate folding trajectories of the amphiphilic copolymers and supported the single-chain folding model proposed with conformational details. The interaction and self-assembly of hydrophobic side chains in the solid state were evidenced by NMR relaxometry studies of 1H and 19F nuclei. Moreover, the nanostructured, outer surface of thin copolymer films was shown to be preferentially populated by
perfluoralkyl chains by angle-resolved X-ray photoemission spectroscopy (AR-XPS) analyses.
Amphiphilic hydrolysable RAFT block copolymers were synthesised with the aim to develop surface-active materials for new marine antifouling/fouling release coatings. Low elastic modulus and low surface energy were key parameters of the coating envisaged to combat fouling in a way to interfere with aquatic foulant adhesion and favour the biomass removal. These two features were combined in a silicone matrix-based coating that contained the surface-active amphiphilic copolymer carrying labile trialkylsilyl ester moieties at
6 the surface of the film. Wettability of model coatings was investigated with sessile drop and captive air bubble contact angle measurements. Antifouling and fouling release properties were assessed during a campaign of field immersion tests in natural seawater in Toulon (France) bay by regular inspection of coatings during seventeen weeks. Adhesion of different foulants, including biofilm, soft foulants and hard foulants, was evaluated with an efficacy factor to estimate the antifouling performance. Removal of adhered biomass was also evaluated by sponge cleaning the coatings, which permitted to estimate the bounty of the fouling-release performance.
CONVEGNI, WORKSHOP E SEMINARI IN ITALIA E ALL’ESTERO/ CONFERENCES, WORKSHOPS,
SEMINARSATTENDED IN ITALY AND ABROAD (indicare denominazione, sede, data e se la
partecipazione ha previsto anche la presentazione di un contributo / please provide the name, the
location, the date and whether the participation included also the presentation of a contribution)
1. Workshop "Year of Light 2015 - The chemical point of view", DCCI UNIPI 9-10/02/20152. Workshop “La misura del Potenziale Zeta di Superfici Solide”, DCCI UNIPI 17/09/2015
3. EPF 7th summer school “Polymers at interphases and surfaces” Gargnano 17-22/05/2015 (Flash presentation + poster)
4. European Polymer Federation congress EPF 2015, Dresden 21-26/06/2015 (Poster) 5. EuroPolymer Conference 2016, Gargnano 22-26/06/2016
6. Chemistry for future 2016, DCCI UNIPI, Pisa 7-9/09/2016
7. XXII Convegno nazionale dell’associazione italiana di scienza e tecnologia delle macromolecole - AIM, Genova 11-14/09/2016 (Oral comunication)
8. European Polymer Federation congress EPF 2017, Lyon (France) 2-7/07/2017 (Poster) 9. Italian-Nordic Polymer Future, Pisa 14-15/09/2017 (Poster)
EVENTUALE ATTIVITÀ DI RICERCA IN AZIENDA / SUBSEQUENT RESEARCH ACTIVITIES IN
COMPANIES (indicare denominazione, ente ospitante, periodo e luogo di svolgimento, eventuale
supervisore aziendale, attività svolte e risultati / please indicate the name, the hosting institution,
the period and duration of the activity, the subsequent company supervisor, activities carried out
and results)
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PUBBLICAZIONI (N.B. depositate in ARPI) / PUBLICATIONS (Note: Publications must be stored in
ARPI
TIPOLOGIA PUBBLICAZIONE (articolo, proceeding, monografia, edizione fonti…) TYPOLOGY (article, proceeding, monography, source edition…) ALTRI AUTORI COAUTHORS TITOLO DELLA PUBBLICAZIONE TITLE ESTREMI DELLA PUBBLICAZIONE (rivista,editore, convegno, altro) PUBLICATION DETAILS (journal title, publishing company, conference title
and so on)
ISSN/ISBN
Article Martinelli E.,
Guazzelli E., Bartoli, C., Gazzarri M., Chiellini F., Galli G., Callow M.E., Callow J.A., Finlay J.A., Hill S. Amphiphilic Pentablock Copolymers and Their Blends with PDMS for Anti-biofouling Coatings
J. Polym. Sci. A Polym. Chem., 2015, 53, 1213– 1225 0887-624X Poster E. Guazzelli, E. Martinelli, C. Bartoli, M. Gazzarri, F. Chiellini, G. Galli, M.E. Callow, J.A. Callow, J.A. Finlay, S. Hill Polysiloxane, polyethylene glycol and polyperfluoroacrylate pentablock
copolymers for anti-biofouling coatings, EPF2015 congress Dresden Poster + Flash presentation E. Guazzelli, E. Martinelli, C. Bartoli, M. Gazzarri, F. Chiellini, G. Galli, M.E. Callow, J.A. Callow, J.A. Finlay, S. Hill Amphiphilic pentablock
copolymers and their blends with PDMS for biofouling-release coatings
EPF 7th summer school Gargnano 2015 Polymers at interphases and surfaces Poster E. Guazzelli, E.Martinelli, G. Galli, F. Domenici, G. Paradossi. Amphiphilic tetraethylene glycol methacrylate-perfluoroalkyl acrylate block and random copolymers: Synthesis and self-assembling in water
8 solution. Oral communication + conference proceedings E. Guazzelli, E.Martinelli, G. Galli. Sintesi e caratterizzazione, in soluzione e di superficie, di copolimeri anfifilici statistici e a blocchi di tetraetilenglicol metacrilato e perfluoroesiletil acrilato. XXII Convegno nazionale dell’associazione italiana di scienza e tecnologia delle macromolecole - AIM, Genova 11-14/09/2016 Poster E. Guazzelli, E. Martinelli, E. Masotti, M. Borelli, A. Pucci, F. Domenici, G. Paradossi, G. Galli, Single-chain folding and self-assembly of amphiphilic random copolymers in water.
EPF congress 2017, Lyon
Poster E. Guazzelli, E. Masotti, E. Martinelli, F. Domenici, G. Paradossi, G. Galli Unimer micelles of amphiphilic random copolymers by single-chain folding in water Italian-Nordic Polymer Future 2017, Pisa Article E. Guazzelli, E. Masotti, T. Biver, A. Pucci, E. Martinelli, G. Galli, , The Self-Assembly over Nano- to Submicro-Length Scales in Water of a Fluorescent Julolidine-Labeled Amphiphilic Random Terpolymer
J. Polym. Sci. A Polym. Chem., 2018, DOI: 10.1002/pola.28955
0887-624X
PUBBLICAZIONI (in corso di pubblicazione) / PUBLICATIONS (submitted but not yet published)
TIPOLOGIA PUBBLICAZIONE (articolo, proceeding, monografia, edizione fonti…) TYPOLOGY: ( article, proceeding, monography, source edition…) ALTRI AUTORI / COAUTHORS TITOLO DELLA PUBBLICAZIONE TITLEESTREMI DELLA PUBBLICAZIONE
(rivista, editore, convegno, altro)
PUBLICATION DETAILS
(journal title, publishing company, conference title and so on)
Article E. Martinelli, L. Annunziata, E. Guazzelli, A. Pucci, T. Biver, G. Galli The temperature-dependent nano-assemblies of amphiphilic random copolymers carrying poly(oxyethylene) and poly(siloxane) pendant chains Macromolecular rapid communications
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