P. Balsorano, MD
DEPARTMENT OF ANESTHESIA AND INTENSIVE CARE MEDICINE Division of Oncological Anesthesia and Intensive Care
AOU CAREGGI, Florence, Italy
Storia naturale delle trombosi
catetere correlate:
CRT: Symptomatic: 0-28%; Asymptomatic: 25-71%
Baumann Kreuziger L et al. Thromb Res. 2017
Incidenza: 0-71%
Baumann KL et al. Thromb Res. 2017 Sep;157:64-71
Magnitude of the problem
0-3%
0.8
0.85
0.9
0.95
1.0
0
5
10
15
20
25
30
30-Day UE VTE for type of line
Days
Up
p
er
E
xt
re
m
it
y
D
V
T
-Fr
ee
S
u
rv
iv
al
None
CVC Only
PICC only
Both
When?
0.8
0.85
0.9
0.95
1.0
0
5
10
15
20
25
30
30-Day UE VTE for type of line
Days
Up
p
er
E
xt
re
m
it
y
D
V
T
-Fr
ee
S
u
rv
iv
al
None
CVC Only
PICC only
Both
0.8
0.85
0.9
0.95
1.0
0
5
10
15
20
25
30
30-Day PE for Any line versus No line
Days
Up
p
er
E
xt
re
m
it
y
D
V
T
-Fr
ee
S
u
rv
iv
al
No line
Yes line
Pulmonary embolism
Kang J et al. Vasc Access. 2017 Mar 21;18(2):153-157.
PTS
PTS
Thiyagarajah K et al. Thromb Res. 2019 Feb;174:34-39
6-37% after UEDVT
Real problem?
Is it relevant?
Long term disability
E.E. Elman et al. Thromb. Res. 117 (6) (2006) 609–614
Not frequent after catheter-related
UEDVT
Recurrence
..and now?
146 pts
with CVC
placement
22% CRT
1% PTS
2-year follow up
Jones S et al. Blood. 2019 Feb 21;133(8):857-866.
O'Brien S. Blood. 2019 Feb 21;133(8):776-777