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Learning at the Leaning tower

Pisa Colorectal Cancer 2017

Pisa, 30

th

November-1

st

december 2017

RESIDENTIAL COURSE

direCTOR

Alfredo Falcone

SECTION OF ONCOLOGY

7,7 CME POINTS

With the patronage of

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Aims

The goal is to provide an adjourn and discuss on the current scientific evidence concerning standard and new therapeutic strategies in colorectal cancer with a special attention to biological knowledge of treatments and translational research. Lectures and presentations of National and International experts will give large prospects in systemic and locoregional approaches of early and advanced phases.

Addressed to

Physicians specialized in anatomical pathology, gastroenterology, oncology, pharmacology, radiology, radiotherapy and surgeons involved with epidemiological, diagnostic, histopathological, biomolecular and instrumental management and treatment of patients affected by colorectal cancer; biologists.

It won’t be possible give credits to physicians specialized in different fields.

CME

Based on Italian regulations, Accademia Nazionale di Medicina (provider n. 31), will assign to the activity CME (31-199254): 7,7 CME points.

The credit certification is subject to:

• professions/specializations should correspond to those which have been accredited for CME;

• 90% attendance to the meeting;

• Completion of the meeting evaluation form;

• Completion of the final questionnarie ( at least 75% of correct answers).

We would like to remind that only 1/3 of the CME credits acquired during the years 2017- 2019 can come from a sponsorship.

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Registration

The registration fee is € 150,00 for physicians and € 50,00 for resident physicians, tax free. Under the article 54 T.U.I.R and within the limits set out therein, the costs of participation in this activity are deductible in determing self- imployment income.

To register, please send:

• registration form duly filled out (even when sponsored by a pharmaceutical company);

• privacy statment and consent to the use of personal data;

• payment;

• for resident physicians, a Certificate of attendance signed by the School Director

to Accademia Nazionale di Medicina, Galleria Ugo Bassi 2, 40121

Bologna (fax + 39 051 0569162, email: [email protected]) within November 20th 2017.

Payment can be done by:

• non-transferable check addressed to Accademia Nazionale di Medicina,

• bank transfer addressed to:

Accademia Nazionale di Medicina, Banco Popolare - IBAN:

IT11M0503401405000000000966 - SWIFT(BIC) CODE: BAPPIT22 (please indicate “Registration of Dr …. at Course 17_RE_2487)

• credit card MasterCard, Visa, EuroCard (no AMEX cards).

Otherwise it is possible to register online at www.accmed.org, without forgetting to send the wire transfer receipt or the credit card details by fax +39 051 0569162.

Requests received without proof of payment and/or incomplete card won’t be considered valid. The registration will be confirmed by the Secretariat by mail.

CANCELLATION

• If the participants minimum number is not reached, Accademia Nazionale di Medicina will advise all participants by email and proceed with the total refund of the fee.

• In order to cancel please give advise with a written communication to Accademia Nazionale di Medicina within 10 days from the beginning. A 70%

registration fee will be returned.

Any cancellation after that deadline won’t be reimbursed.

FELLOWSHIPS

Some fellowships will be awarded which will include registration, 1 night, 1 dinner and travel.

Those interested should send the registration form together with a short CV and a motivation letter within November 1st. The Organizing Secretariat will confirm you the award of fellowship within November 15th and it will proceed with the logistics.

Official Language

The official language of the Meeting is English. No simultaneous translation will be provided.

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Program

THURSDAY, 30

th

NOVEMBER

9.00 Participants’ registration 9.30 Introduction and welcome

Alfredo Falcone and Authorities (Paolo Mancarella - University of Pisa,

Carlo Tomassini - Azienda Ospedaliero-Universitaria Pisana, Gianni Amunni - Istituto Toscano Tumori) I SESSION

From lab to clinic: the daily challenge of translational research in CRC

Chairmen:

Gabriella Fontanini, Carmine Pinto

10.00 Biomarkers in mCRC today:

what’s needed?

Filippo Pietrantonio

10.15 Biomarkers in mCRC tomorrow: what’s on the horizon?

Andrea Sartore Bianchi 10.30 Liquid biopsies to optimize

the treatment: are we ready?

Alberto Bardelli

10.45 Pharmacogenomic hints to prevent toxicity: practical points

Romano Danesi, Marzia Del Re 11.00 Discussion 11.30 Coffee break

SCIENTIFIC SYMPOSIUM Meet the experts

Future is now: translational research in mCRC

Chairmen: Stefano Cascinu, Alfredo Falcone

12.00 LECTURE

Targeted therapies: what can we expect in the next future?

Rodrigo Dienstmann 12.40 Round Table and debate

with Italian experts Shooter: Chiara Cremolini Experts: Antonio Avallone, Alberto Bardelli,

Filippo De Braud, Francesco Di Costanzo, Salvatore Siena

13.20 Lunch 14.20 LECTURE

Immunotherapy: ready for prime time in colorectal cancer?

Johanna Bendell

15.00 Round Table and debate with Italian experts Shooter: Filippo Pietrantonio Experts: Giuseppe Aprile, Roberto Labianca, Sara Lonardi, Evaristo Maiello, Giuseppe Tonini 15.40 Coffee break

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FRIDAY, 1

st

DECEMBER

II SESSION

Localized colon and rectal cancer: open questions Chairmen: Luca Morelli, Francesco Di Costanzo 16.15 How to improve the

estimation of the risk of relapse? Helps from the lab Francesco Leone

16.30 When is TME too much?

Is there room for

conservative approaches in rectal cancer?

Matteo Franceschi 16.45 Adjuvant chemo

following neoadjuvant chemoradiotherapy: when to go and when not to go?

Carlo Aschele

17.00 Practical points for the experts

Carlotta Antoniotti 17.30 Discussion 18.00 Adjourn

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III SESSION

Systemic treatment of mCRC Chairmen:

Giordano D. Beretta, Stefano Cascinu

9.00 The upfront treatment of mCRC: my algorithm Alfredo Falcone

9.15 Primary tumour location:

the methodologist’s perspective Luca Boni

9.30 Primary tumour location:

the oncologist’s perspective Mario Scartozzi

9.45 Practical points for the experts

Roberto Moretto

10.05 Discussion 10.25 Coffee break 11.00 Treatments after

progression: how to choose?

Giuseppe Aprile

11.15 The new landscape of later lines: to go or not to go?

Sara Lonardi

11.30 Practical points for the experts

Emiliano Tamburin 11.50 Discussion 12.10 LECTURE

Presenter: Roberto Labianca Adjuvant treatment of colon cancer: past, present and future

Julien Taieb

13.00 Lunch IV SESSION

The cure as an objective:

liver-limited and

oligometastatic colorectal cancer

Chairmen: Giacomo Allegrini, Gianluca Masi 14.00 “Systemic arrows”: the

oncologist’s contribution Lisa Salvatore

14.15 “Surgical arrows”: old and new surgical options Dario Ribero

14.30 “Locoregional arrows”: new options from interventional radiology

Irene Bargellini

14.45 “Locoregional arrows”: the radiotherapist’s perspective Francesco Pasqualetti 15.00 Practical points for the

experts

Federica Marmorino 15.30 Discussion

16.00 Adjourn and final questionnaire

FRIDAY, 1

st

DECEMBER

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director

Alfredo Falcone

Department of Oncology, Transplants, and New Technologies in Medicine University of Pisa

Division of Medical Oncology University Hospital of Pisa (I)

Scientific Secretary

Chiara Cremolini Department of Oncology,

Transplants and New Technologies in Medicine

University of Pisa (I) Gianluca Masi

Division of Medical Oncology University Hospital of Pisa (I)

Speakers

Giacomo Allegrini, Pisa (I) Carlotta Antoniotti, Pisa (I) Giuseppe Aprile, Vicenza (I) Carlo Aschele, La Spezia (I) Antonio Avallone, Naples (I) Alberto Bardelli, Candiolo – TO (I) Irene Bargellini , Pisa (I)

Johanna Bendell, Nashville (USA) Giordano D. Beretta, Bergamo (I) Luca Boni, Florence (I)

Stefano Cascinu, Modena (I) Chiara Cremolini, Pisa (I) Romano Danesi, Pisa (I) Filippo De Braud, Milan (I) Marzia Del Re, Pisa (I)

Francesco Di Costanzo, Florence (I) Rodrigo Dienstmann, Barcelona (S) Gabriella Fontanini, Pisa (I) Matteo Franceschi, Paisa – PI (I)

Roberto Labianca, Bergamo (I) Francesco Leone, Candiolo – TO (I) Sara Lonardi, Padua (I)

Evaristo Maiello, Foggia (I) Federica Marmorino, Pisa (I) Gianluca Masi, Pisa (I) Luca Morelli, Pisa (I) Roberto Moretto, Pisa (I) Francesco Pasqualetti, Pisa (I) Filippo Pietrantonio, Milan (I) Carmine Pinto, Reggio Emilia (I) Dario Ribero, Milan (I)

Lisa Salvatore, Pisa (I)

Andrea Sartore Bianchi, Milan (I) Mario Scartozzi, Cagliari (I) Salvatore Siena, Milan (I) Julien Taieb, Paris (F)

Emiliano Tamburini, Rimini (I) Giuseppe Tonini, Rome (I)

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Meeting Venue

Auditorium G. Toniolo Opera della Primaziale Pisana Piazza Arcivescovado, 1 Pisa

How to reach the meeting venue:

BY CAR: No matter which highway you're on (A1 from Rome, A11 from Florence, A12 from Genova), get off at the Pisa Nord exit then find your way to a parking lot-most of Pisa's historic center is now ZTL ("Zona Traffico Limitato" - only residents with permits are allowed to drive into it). There's a public parking lot just a block up from the western edge of the Campo dei Miracoli on Via Pietrasanta.

BY TRAIN: From the train station, you can take one of these buses

LAM ROSSA – stop at via Cammeo/Piazza Manin N. 4 – stop at Piazza Arcivescovado N. 21 night bus –stop at Piazza Manin BY PLANE: From the airport, you can take:

LAM ROSSA – stop at via Cammeo/Piazza Manin N. 21 night bus – stop at Piazza Manin

Sponsored by

ACCADEMIA NAZIONALE DI MEDICINA

General Manager: Stefania Ledda Information and registration:

www.accmed.org Ph. +39 051 0569163 Fax +39 051 0569162 [email protected]

Organizing Partner

Forum Service

Via Martin Piaggio 17/6 16122 Genova

Hotel booking

Ph. +39 010 83794244 Fax +39 010 83794261 [email protected]

With the unconditional contribution of

GOLD SPONSOR

BRONZE SPONSOR

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