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2019:

PRECISION

ONCOLOGy

THE DATE SAVE

24-25 May 2019 ROME

HOTEL QUIRINALE, Via Nazionale 7

PROGRAMME

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CONGRESS LOCATION

The conference takes place in Rome, at the Hotel Quirinale (Via Nazionale, 7 Tel: 06 4707) on 24 and 25 May 2019. The Organizing Secretariat is available to participants at the conference venue from 9.00 am on 24 May and for the whole duration of the event.

SUBSCRIPTIONS

Subscription entitles to participation in scientific work, to receiving the folder containing scientific documents, the attendance certificate and the admission to working lunch.

ATTENDANCE CERTIFICATE

The attendance certificate will be given to all participants regularly registered in the course, who will request it at the secretary desk at the end of the work.

ECM

For this course the Commissione Nazionale per la Formazione Continua in Medicina (National Commission for Refresher Courses in Medicine) (ECM) of the Ministry of Health assigns, n. 7.7 training credits for the following professional figures of PHYSICIAN AND SURGEON (oncology, pathological anatomy, pharmacology and clinical toxicology, gynaecology and obstetrics, general surgery, radiation therapy, medical technician of biomedical laboratory, urology, clinical biochemistry, medical genetics), BIOLOGIST and NURSE.

To obtain the ECM credits, it is necessary to participate in at least 90% of the scientific papers, completely fill out the ECM dossier, correctly answer to at least 75% of the questions and return the dossier to the organizational secretariat at the end of the work. Upon completing the training activity, the participant will be given an attendance certificate while the certificate showing the ECM credits will be sent after the completion of the procedure so that the questionnaires can be corrected. Speakers are entitled to 1 credit for every half hour of teaching regardless of the credits assigned to the event.

GENERAL

INFORMATIONS

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FACULTY

Roberto Bordonaro P. O. Garibaldi-Nesima, Catania

Emilio Bria

Università Cattolica del Sacro Cuore, Fondazione Policlinico ‘A. Gemelli’, Roma

Ettore Capoluongo

U.O.S.D. Fondazione Policlinico

‘A. Gemelli’, IRCCS, Roma

Carlo Carnaghi Humanitas Mater Domini, Castellanza (VA)

Giacomo Cartenì A. O. Cardarelli, Napoli

Vanna Chiarion Sileni Istituto Oncologico Veneto, Padova

Saverio Cinieri A.S.L. Brindisi

Francesco Cognetti I.F.O. Regina Elena IRCCS, Roma

Pierfranco Conte Istituto Oncologico Veneto, Padova

Laura Cortesi

A.O. Policlinico Universitario, Modena

Romano Danesi Università degli Studi, Pisa

Emanuele De Luca

Azienda Ospedaliera- Universitaria an Luigi Gonzaga,

Orbassano (TO Gaetano De Rosa

Università Federico II - Napoli Angelo Del Monte

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.), Meldola (FC)

Marzia Del Re Ospedale S. Chiara, Pisa

Massimo Di Maio A.O. Ordine Mauriziano, Torino

Alessandra Fabi I. F. O. Regina Elena, Roma

Stefania Gori

Presidente Nazionale AIOM,

Direttore Oncologia Medica - IRCCS Ospedale Sacro Cuore - Don Calabria, Negrar (VR)

Francesco Grossi Ist. Naz. Ricerca Cancro, Genova

Valentina Guarneri

Istituto Oncologico Veneto IRCCS, Padova

Lorena Incorvaia

A.O.U. Policlinico “Paolo Giaccone”, Palermo

Alessandro Inno

IRCCS Ospedale Sacro Cuore - Don Calabria,

Negrar (VR) Nicla La Verde

A.S.S.T. Fatebenefratelli Sacco, Milano

Giuseppe Lombardi Istituto Oncologico Veneto, Padova

Sara Lonardi

Istituto Oncologico Veneto, Padova

Giuseppe Lo Russo

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano,

Milano Vito Lorusso

Istituto Tumori Giovanni Paolo II, Bari

Claudio Luchini Università degli Studi, Verona

Antonio Marchetti Università G. D’Annunzio, Chieti

Paolo Marchetti

Azienda Ospedaliero-Universitaria Sant’Andrea,

Roma

Marco Merlano A. O. S. Croce e Carle, Cuneo

Enrico Mini A.O.U. Careggi, Firenze

Giorgio Minotti

Università Campus Bio-Medico, Roma

Filippo Montemurro Istituto di Candiolo IRCCS, Candiolo (To)

Federica Morano

Fondazione IRCCS Istituto Nazionale Tumori,

Milano

Emanuele Neri

Istituto Dipartimento di Ricerca Traslazionale, Università di Pisa Fabrizio Nicolis

Presidente Fondazione Aiom, IRCCS Ospedale Sacro Cuore - Don Calabria,

Negrar (VR)

Giuseppe Procopio

Fondazione IRCCS Istituto Nazionale dei Tumori,

Milano

Paola Queirolo A.O.U. S. Martino, Genova

Luigi Ruco

Università La Sapienza, Roma

Antonio Russo

A.O.U. Policlinico P. Giaccone, Palermo

Stefano Severi IRST-IRCCS, Meldola (FC) Nicola Silvestris Ospedale Giovanni Paolo II, Bari

Valentina Sini

ASL Roma1 UOSD Centro Oncologico, SS-NRM,

Roma

Pierfrancesco Tassone Università Magna Graecia, Catanzaro

Giuseppe Toffoli C.R.O.,

Aviano (PN) Stefania Tommasi

IRCCS-OSPEDALE ONCOLOGICO, Bari

Giancarlo Troncone

Università degli Studi “Federico II”, Napoli

Elena Vigliar Università Federico II, Napoli

Vittorina Zagonel

Istituto Oncologico Veneto IRCCS, Padova

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PROGRAMME

24 MA Y

SESSION I A CHANGING WORLD…

Moderators: F. Cognetti, L. Ruco

10.00 From histology to the molecular profile:

integrated diagnostic approach to neoplasms C. Luchini

Response Predictive factors to immunotherapeutic drugs from PDL-1 to Tumor Mutational Burden:

- 10.15 the pathologist G. Troncone, E.Vigliar - 10.25 the pharmacologist R. Danesi 10.35 The tumor microenvironment and new drugs

F. Cognetti 10.50 Discussion

SESSION II UNANSWERED QUERIES

Moderators: M. Merlano, E. Mini

11.00 “Driver” mutation and “Passenger” mutation:

what is the clinical meaning?

S. Tommasi

11.15 The new immune-related response criteria (iRECIST):

are always adequate G. Lo Russo

11.30 The design and conduct of clinical trials in the era of precision oncology:

what is changing?

E. De Luca, M. Di Maio 12.00 Discussion

SESSION III BRCA MUTATED OVARIAN CARCINOMA

Moderators: G. De Rosa, N. La Verde

12.00 AIOM-SIGU-SIBIOP-SIAPEC-IAP 2019 recommendations L. Cortesi

12.15 The use of new genomic technologies in BRCA mutated ovarian cancer patients: what information?

E. Capoluongo

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12.30 Germinal pharmacogenetics G. Toffoli

12.45 Discussion 13.30 Working Lunch

SESSION IV ONCOGENE-ADDICTED NSCLC

Moderators: F. Grossi, A. Inno

14.30 The development of resistances:

clinical impact and therapeutic strategies M. Del Re

14.45 Liquid biopsy recommendations AIOM -SIAPEC-IAP-SIF-SIBioC A. Russo

15.00 Criteria of response during therapies in TKI:

clinical or molecular criteria?

E. Bria

15.15 The new targets: ROS1, MEK, NTRK A. Del Monte

15.30 Discussion

SESSION V COLORECTAL CARCINOMA

Moderators: C. Carnaghi, V. Zagonel

16.00 Definition, effect, clinical course, therapies S. Lonardi

16.15 New therapies and scientific evidence F. Morano

16.30 Position of regulatory bodies: FDA, EMA, AIFA R. Bordonaro

16.45 Discussion

PROGRAMME

24 MA Y

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SESSION VI MALIGNANT MELANOMA, CEREBRAL AND UROLOGICAL NEOPLASMS

Moderators: G.Cartenì, P. Queirolo

17.15 2019: adjuvant treatment of malignant melanoma V.Chiarion Sileni

17.30 New targets in brain neoplasms G. Lombardi

17.45 BRCA2 and prostate carcinoma G. Procopio

18.00 Urological malignancies and immunotherapy: which targets?

L. Incorvaia

18.15 Discussion

18.30 Conclusion of works

PROGRAMME

24 MA Y

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PROGRAMME

24 MA Y

SESSION VII BREAST CANCER

Moderators: S. Cinieri, S. Gori

8.30 PI3KA mutations and ER mutations:

what impact on the outcome of breast cancer patients?

- the pharmacologist G.Minotti - the oncologist A. Fabi

9.15 BRCA mutated metastatic breast cancer:

What is the role of PARP-I?

V.Guarneri

9.30 Immunotherapy in breast cancer: what evidence?

V. Sini 9.45 Discussion

Sessione VIII NEW FRONTIERS

Moderators: V. Lorusso, S.Severi 10.00 Radio receptor therapy

S.Severi 10.20 Radiomics

E. Neri 10.40 Discussion 11.00 Coffee Break

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25 MA Y

PROGRAMME

SESSION IX THE AGNOSTIC-TISSUE PRECISION MEDICINE: AN EMERGING APPROACH

Moderators: N.Silvestris, P. Tassone

11.30 Rational and therapeutic bases P. Marchetti

11.45 New targets: are they always clinically useful?

F. Montemurro

12.00 Ongoing clinical studies P. Marchetti

12.15 Patients’ requests F. Nicolis

12.30 Reading: The importance of interdisciplinary working groups in the age of precision oncology. The Molecular Tumor Board (MTB):

from clinical indications to regulatory contexts P. Conte

12.50 Discussion

13.15 Conclusions

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PROGRAMME PARALLEL SESSION

25 MA Y

PARALLEL SESSION AIOM FOUNDATION MEETS PATIENTS AND CITIZENS

Moderator: F. Nicolis

09.00 Precision oncology: characterize the tumor to decide on the appropriate treatment

A. Marchetti

09.15 Molecular target therapies in oncology: what results?

A. Russo

09.30 Immunotherapy in oncology: results and perspectives A. Fabi

09.45 Discussion

Patients ask … oncologists answer

11.30 Conclusions

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Sede di Roma

Via Domenico Cimarosa 18 - 00198 Roma Tel. 068553259 - Fax 068553221

[email protected] Sede di Milano

Via Enrico Nöe 23 - 20133 Milano Tel. 0226683129 - Fax 0259610555

[email protected]

SEGRETERIA ORGANIZZATIVA AIOM Servizi Srl

Servizi Provider ECM

ISO 9001

AIOM

Via Enrico Nöe 23 - 20133 Milano Tel. 0270630279 - Fax 022360018

[email protected] www.aiom.it

FONDAZIONE AIOM Via Enrico Nöe 23 - 20133 Milano Tel. 0226683335 - Fax 0259610555

[email protected] www.fondazioneaiom.it

GRAZIE ALLA SPONSORIZZAZIONE NON CONDIZIONANTE DI:

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