A
ABCG2 40
ACAID (Anterior chamber associated immune deviation) 110
Acanthamoeba keratitis 153, 196 Adenoviral keratoconjunctivitis
see keratoconjunctivitis Air drying 25
Airdissection 67 Albumin 17 Allergen 214
Allergic eye disease 209 Allograft rejection 65 Allorecognition 110 – direct pathway 76, 110 – indirect pathway 110 Amnion 22
– composition 22 – structure 22 Amniotic epithelium 26
Amniotic membrane 21, 49, 51, 52, 57, 58 Amphotericin B 0.15% 158
Anecortave acetate 95 Angiogenesis 83
Angiogenic growth factor see growth factor Aniridia 83
Anterior chamber associated immune deviation see ACAID 110
Antiangiogenic therapy 83 Anticoagulant 6
Antigen presenting cells (APCs) 76, 105 Antihistamine 217, 218
Antilymphangiogenic therapy 83 Antithymocyte globulins 117 APCs (antigen presenting cells) 105 Arlt’s lines 215
Artificial anterior chamber 129 Asthma 209
Astigmatism 123, 136 – irregular 123, 124
Atopic keratoconjunctivitis see kerato- conjunctivitis
Auto-limbal transplantation 48, 50
Autologous serum 1 – eyedrops 4, 52
Autologous transplantation 59 Avastin 95
Azathioprine 112 B
Bandage contact lens 51 Basal cells 184
Basement membrane 24, 58 Basiliximab 112, 117 Bioengineering 57
Biomicroscopy, slit-lamp 174 Blood group antigen 106 Blood product 6 Bowman’s membrane 187 Broad antigen 102 Buccal mucosa graft 35 Bullous keratopathy 30 C
Calcineurin inhibitor 220 Candida albicans 159 Caustication 61 CD4+ T cells 110, 212 CD8+ T cells 110, 212 Centration 123, 134 Certican 116 Chemical burns 83 Chronic limbitis 41 Cidofovir 163, 168 – topical 167 Collagen 22, 52 Conjunctiva 177
Conjunctival hyperreactivity – non-specific 211 Conjunctivalisation 35 Conjunctivitis
– giant papillary 209, 217 – perennial allergic 209, 214 – seasonal allergic 209, 213, 214 Connexin 43
Contact lens 83, 90, 173, 192
Contamination 15
Corneal angiogenic privilege 84
Corneal basement membrane dystrophy 13 Corneal dissection
– laser 68 – manual 68
Corneal epithelial thickness 173 Corneal epithelium 58, 180 – basal cells 180
– Bowman’s membrane 180 – intermediate cells 180 – stroma 180
– superficial cells 180 Corneal lymphatic vessel 94 Corneal nerve 173, 185 Corneal oedema 75 Corneal opacity – nummular 165 – persistence 168 – subepithelial 165 Corneal perforation 28
Corneal surgery, refractive 173, 200 Corneal transplantation 88 Corneal ulcer 144, 199 Corneoscleral tissue 59 Corticosteroid 52, 114 – topical 219 Cortisone 112 Cryopreservation 26 Cut angle 129 Cyclophosphamide 112
Cyclosporin A (CsA) 52, 109, 112, 114, 118, 163, 220 – topical 169
– eyedrops 98
Cystic epithelial change 191 Cytokeratin profile 39 Cytotoxic T lymphocyte 77 D
Daclizumab 112, 117
Delayed type hypersensitivity 77 Dendritic cells 173, 209
Dennie-Morgan fold 216 Descemet’s membrane 188 Digital photography 175 Donor 123
Dry eye 5, 8, 10, 11, 190 Dystrophy 144 – stromal 144 E
Embryonic stem cells 37 Endothelial cells 188 – density 66
Epidemic keratoconjunctivitis see keratoconjunctivitis
Epitheliotrophic factor 1, 2, 3, 5 Epithelium 42, 57, 181 – conjunctival 58
– corneal see corneal epithelium Erbium: YAG Laser 147 Everolimus 109, 116 Excimer Laser 193-nm 144
Extracapsular cataract extraction 138 Extracellular matrix 37
F Fibrin 52
Fibroblast feeder layer 58 Fibronectin 2, 22 FK506 112, 114, 220 Flap lift 153, 155 Flieringa ring 133 Fluoroquinolone 158 FTY 720 116
Fuchs’s endothelial dystrophy 111, 129, 145 Functional imaging 173, 203
Fungal infection 153 G
Gas-permeable lens 217 Gatifloxacin 158
Giant papillary conjunctivitis see conjunctivitis
Glutaraldehyde 25 Goblet cell 58 Graft failure 144 Graft rejection 105 Graft size 123, 129, 133 Graft survival 102
Gram-negative organism 153 Growth factor 5, 23, 24 – angiogenic 86 – TGF-b1 26
Guided trephine system see trephine H
HA-3 105
Hand-held trephine see trephine Hanna trephine see trephine Hay fever (see also conjunctivits,
seasonal allergic) 213
Herpes simplex keratitis see keratitis Hertoge’s sign 216
HLA 102
– class I molecules 102 – class II molecules 102 – matching 52, 61, 78, 102 – typing 52, 102 HLAMatchmaker 102 – algorithm 104, 107 Horizontal torsion 127
Horner-Trantas dot 215 H-Y 105
Hypersensitivity type I 210 I
IL (Interleukin)-1 114 – inhibition 221 IL-2
– antagonist 112 – inhibitor 109 IL-6 114
Immune privilege 76 Immune rejection 94 Immunoglobulin E 210
Immunomodulatory cytokine 94 Immunosuppressive molecule 76 Immunosuppressive strategy 109 Impression cytology 39, 60 Infiltrates 165
Inflammation 29 Inflammatory cells 173 Instrastromal ring segment 67 Interface haze 65, 68
Interferon 163, 169
Interleukin (see also IL) 210 Intermediate cells 184 Intraoperative adjustment 123 Irradiation 25
K
Keratectomy, phototherapeutic (PTK) 67, 129 Keratinisation 43
Keratitis 83, 158, 159 – acanthamoeba 196
– diffuse lamellar (sands of the Sahara) 154 – fungal 158
– herpes simplex 69, 91, 118, 159, 216 – infective 153
Keratoconjunctivis – adenoviral 163 – atopic 209, 215 – epidemic 195 – limbal 215 – superior limbic 13 – vernal 209, 214
Keratoconus 67, 69, 111, 123, 136, 144, 216 Keratocytes
– viral persistence in 195 Keratometric refractive power 124 Keratometry 125
Keratopathy 129
– aphakic/pseudophakic bullous 129, 144 Keratoplasty 64, 129
– deep anterior lamellar 65, 69 – high-risk 90, 109
– indications 144 – low-risk 94, 104
– penetrating 65, 69 – posterior lamellar 129, 148 Keratoprothesis 64 Keratotomy – radial 138 L
Laminin 22
Langerhans cells 52, 105, 177, 184 Laser 123
– femtosecond 123, 148 LASIK 123, 153 Leflunomide 112 Limbal stem cells 35 – culture 57 – deficiency 35, 111 – causes 41
– ex vivo expansion 52, 57 Limbal epithelial crypt 40 Limbal palisades of Vogt 38, 44 Limbal region 188
Limbal transplantation 45 Lymphangiogenesis 83 Lymphocytes
– CD4+ T cells 110, 212 – CD8+ T cells 110, 212 – Cytotoxic T 77 Lyophilisation 25 M
Macrolide antibiotic 220
Macrophage inflammatory protein-1a (MIP-1a) 221
Mapping 125 Mast cell 210 – degranulation 212 – stabilizer 217 – agents 218 Mechnical barrier 76 Meesmann’s dystrophy 190 Metalloprotease 23 – inhibitors 23 Methotrexate 112
MHC (major histocompatibility complex) 102, 110
– class II molecule 76, 210 Microbiological examination 155 – scraping of material 155 Microenvironment 37 Microscopy 173 – confocal 173, 175 – laser-scanning 176 – specular 173 Minor H mismatch 105 Minor matching 102
MIP-1a (Macrophage inflammatory protein-1a) 221 Mismatches, class I and II 78
MMF see mycophenolate mofetil Molecular typing 107 Moxifloxacin 158 Muromonab-CD3 117 Mycobacteria 158 – non-tuberculous 153
Mycophenolate mofetil 52, 109, 112, 114 N
Natamycin 5% 158 Neovascularisation 29, 88 Neurotrophic keratitis 8, 9, 41 – diabetic 9
– postherpetic 9
NMSO3 (sulphated sialyl lipid) 163
Non-steroidal anti-inflammatory drug (NSAID) 219 NSAID (Non-steroidal anti-inflammatory drug) 219 Nummular subepithelial infiltrates 75
O
Ocular surface burn 35
Ocular surface reconstruction 57 P
p63 (transcriptional factor) 39 Pachymetry 194
PCIOL (Posterior chamber intraocular lens) 138 – toric 138
Pemphigoid 41
Perennial allergic conjunctivitis see conjunctivitis
Peritomy 48 Plasma 3, 17
Posterior chamber intraocular lens (PCIOL) 138 Postoperative treatment 65
Progenitor cell 36 Prograf see tacrolismus Proinflammatory cytokine 25 Prostaglandin 25, 219 Proteoglycan 22 Pseudogerontoxon 215 Pterygium surgery 30 Punctual occlusion 11 R
RAD (Everolimus, Certican) 116 Rapamune 115
Rapamycin 52, 109, 115, 118 RCM (Rostock cornea module) 178 Recurrent erosion syndrome 13 Regularity 123
Rejection 73 – acute 110 – chronic 110 – endothelial 73, 75 – epithelial 75 – stromal 75
Rheumatoid arthritis 8
Rubbing 212, 216
– degranulation of the mast cells 212 S
Sands of the Sahara 154 Scarring 29
Seasonal allergic conjunctivitis see conjunctivitis Sequential sector conjunctival epitheliectomy 46 Severe atopic dermatitis 111
Shield cataract 217 Shield ulcer 215 Sirolimus 112, 115, 116 Sjögren’s syndrome 11 Slit-scanning technique 175 – confocal microscopy 175 Stem cells, embryonic 37 Stem cell niche 37, 40 Sodium cromoglygate 218 Split antigen 102 Steroid 109
Steroid, topical 111, 166, 167 Stevens-Johnson syndrome 41 Superficial cells 183
Suture removal 125 Symblepharon 28
Systemic immunosuppression 61 T
Tacrolimus 52, 109, 112, 114, 118, 220 T-cell activation 114
Tear film 42, 182 – dynamics 173 Tear substitute 2 Topical steroid 77 Topography 125 – regularity of 123 TOR inhibitor 109 Toxicity, local 168 Trachoma 41
Transcriptional factor p63 39 Transplant 53
– allo-limbal 53 – auto-limbal 53 Trephination 129 – nonmechanical 129 – techniques 130 – elliptical 137
– nonmechanical laser 143 – host 123
Trephine 138
– guided system 138, 142 – Hanna 143
– hand-held 141 – motor 141 – suction 142 Triple procedure 138 Triplet 104
Tylosis 216
U Ulcer 123
Umbilical chord serum 16 Undercut 131
UV light 212 V
Vascularisation 42, 73 – deep 111
VEGF 85 – trap 95 – aptamer 95
VEGF-A specific cytokine trap 98 Vernal keratoconjunctivitis
see keratoconjunctivitis Vertical tilt 127 Vimentin 39
Viral persistence in the keratocytes 195 Viscodissection 67
Visual acuity 123 W
Waiting period 106 Wing cells 184
